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In reproduction studies with SINEMETno effects on fertility were found in rats receiving doses of approximately two times the maximum daily human dose of carbidopa and four times the maximum daily human dose of levodopa.
Blood in the urine difficult or painful urination changes in mood such as depression forgetfulness signs of anaemiasuch as tirednessbeing short of breathand looking pale signs of frequent or worrying infections such as feversevere chillssore throat or mouth ulcers bruising or bleeding moreeasily than normalnose bleeds fainting skin rashitchiness pinkishitchy swellings on the skinalso called hives or nettle . rash numbness or tingling in the hands or feet signs of melanomasuch as new skin spots or changes to the sizeshapecolour or edges of an existing skin spotfreckle or mole.
All medicines have risks and benefitsYour doctor has weighed the risks of you taking SINEMET against the benefits they expect it will have for you.
If your doctor tells you to stop taking SINEMET or the tablets have passed their expiry dateask your pharmacist what to do with any that are left over.
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