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1 congestive heart failure pioglitazone pioglitazone, like other thiazolidinediones, can cause dose-related fluid retention when used alone or in combination with other antidiabetic medications and is most common when duetact is used in combination with insulin.

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Using this . medicine with any of the following medicines is usually not recommendedbut may be required in some casesIf both medicines are prescribed togetheryour doctor may change the dose or how often you use one or both of the medicines.

This medication is not recommended for use during pregnancyYour doctor may direct you to switch to insulin treatment during your pregnancyUse of pioglitazone/glimepiride close to the expected delivery date may increase the risk of low blood sugar in your newbornConsult your doctor for more detailsand follow all instructions carefully.

This medicine can cause hypoglycemialow blood sugarLow blood sugar can also occur if you delay or miss a meal or snackexercise more than usualdrink alcoholor cannot eat because of nausea or vomitingLow blood sugar must be treated before it causes you to pass outunconsciousnessPeople feel different symptoms with low blood sugarIt is important that you learn which symptoms of low blood sugar you have in order to treat it quicklyTalk to your doctor about the best way to treat low blood sugar.

This is not a complete list of side effects and others may occurCall your doctor for medical advice about side effectsYou may report side effects to FDA at 1-800-FDA-1088.

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