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Controlled clinical studies have shown intranasal corticosteroids may cause a reduction in growth velocity in pediatric patientsThis effect has been observed in the absence of laboratory evidence of hypothalamic-pituitary-adrenalHPAaxis suppressionsuggesting that growth velocity is a more sensitive indicator of systemic corticosteroid exposure in pediatric patients than some commonly used tests of HPA axis functionThelong-term effects of this reduction in growth velocity associated with intranasal corticosteroidsincluding the impact on final adult heightare unknownThe potential forcatch upgrowth following discontinuation of treatment with intranasal corticosteroids has not been adequately studiedThe growth of pediatric patients receiving intranasal corticosteroidsincluding NASONEX Nasal Spray50 mcgshould be monitored routinelye.gvia stadiometryThe potential growth effects of prolonged treatment should be weighed against clinical benefits obtained and the availability of safe and effective noncorticosteroid treatment alternativesTo minimize the systemic effects of intranasal corticosteroidsincluding NASONEX Nasal Spray50 mcgeach patient should be titrated to his/her lowest effective dose.

Thanks , . to Ms Marg Gordonasthma and respiratory educatorand the patient who participated in this film clip.

Systemic effects of nasal corticosteroids may occurparticularly at high doses prescribed for prolonged periodsThese effects are much less likely to occur than with oral corticosteroids and may vary in individual patients and between different corticosteroid preparationsPotential systemic effects may include Cushing’s syndromeCushingoid featuresadrenal suppressiongrowth retardation in children and adolescentscataractglaucoma and more rarelya range of psychological or behavioural effects including psychomotor hyperactivitysleep disordersanxietydepression or aggressionparticularly in children

Dosage is based on your medical condition and response to treatmentYounger children may need a smaller dose and help from an adult to use this medication properlyUse this medication regularly in order to get the most benefit from itTo help you rememberuse it at the same time(seach dayDo not increase your dose or use it more frequently than directed.

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