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Before taking doxepin, tell your doctor if you have used an ssri antidepressant in the past 5 weeks, such as citalopram celexa , escitalopram lexapro , fluoxetine prozac, sarafem , fluvoxamine luvox , paroxetine paxil , or sertraline zoloft .

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This drug has a black box warningThis is the most serious warning from the Food and Drug AdministrationFDAA black box warning alerts doctors and patients about drug effects that may be dangerousThis drug may increase suicidal thoughts or behavior in some childrenteenagersor young adultsThe risk of this is greatest within the first few months of treatment or when the dosage is changedCall your healthcare provider right away if you have new or sudden changes in your moodbehavioractionsthoughtsor feelingsespecially if they are severePay extra close attention when you start taking this drug or when your dosage is changed.

Drugs that interfere with serotonin reuptake inhibitionincluding ZOLOFTincrease therisk of bleeding eventsConcomitant use of aspirinnonsteroidal anti-inflammatory drugsNSAIDsother antiplatelet drugswarfarinand other anticoagulants may add to this riskCase reports and epidemiological studiescase-control and cohort designhave demonstrated an association between use of drugs that interfere with serotonin reuptake and the occurrence of gastrointestinal bleedingBleeding events related to drugs that interfere with serotonin reuptake have ranged from ecchymosishematomaepistaxisand petechiae to life-threatening hemorrhages.

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Efficacy was assessed with the Daily Record of Severity of ProblemsDRSPa patient-rated instrument that mirrors the diagnostic criteria for PMDD as identified in the DSM-IVand includes assessments for moodphysical symptomsand other symptomsOther efficacy assessments included the Hamilton Rating Scale for DepressionHAMD-17and the Clinical Global Impression Severity of IllnessCGI-Sand ImprovementCGI-Iscores.

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a zoloft is a popular drug that is used to treat all kinds of depression disorders and anxiety disorders.