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For immediate-release tablets onlyIf you have a sudden return or worsening of your MS symptomsyou may need to take 200 mg once per day for one weekThis dosage may then be reduced to 80 mg once per day every other day for one month.
You should not stop using prednisone suddenlyFollow your doctor’s instructions about tapering your dose.
For people with heart or kidney diseasePrednisone may make you retain salt and waterwhich can raise your blood pressure.
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25,26 a recent randomized crossover study looking specifically at the effect of prednisone on mood showed no significant differences between patients who received 60 mg of prednisone for 3 days and those who received placebo.